Disclosure and sourcing

PRP Direct is an Emcyte distributor. We have a commercial interest in the systems on this page. That is exactly why every specification here is quoted from the manufacturer's own published documentation and named at the point of use, so you can check it against the source rather than take our word for it.

Where a manufacturer does not publish a figure, we say so instead of estimating. We have not independently tested any device referenced here, and no figure on this page is our own measurement.

Product comparison

PurePRP SP vs Pure Two PRP

Both are Emcyte double-spin PRP systems, and Emcyte's instructions give them the same spin protocol and the same final volume, so platelet counts are comparable. The real difference is the disposable and the bench workflow.

Figures below are manufacturer-reported device specifications, not claims of clinical efficacy of the prepared PRP.

Manufacturer-reported	PurePRP SP	Pure Two PRP
Process	Double spin	Double spin
Spin protocol (60 mL, Executive Series)	2.0 then 4.0 min at 4400 RPM	2.0 then 4.0 min at 4400 RPM
Disposables per case	One integrated device	Two (separator + concentrator)
Counterbalance operations	1	2
Final PRP volume (60 mL kit)	7 mL	approximately 7 mL
Published yield block	≥90% yield, ≥6x baseline, <1% hematocrit	not published separately; comparable counts
Kit sizes	30 / 60 / 120 mL	30 / 60 / 120 mL

Manufacturer-reported, from the Emcyte instructions for use and product pages. Emcyte publishes its numeric yield block for the SP platform and does not publish an equivalent block for Pure Two PRP.

The case for PurePRP SP

SP does both spins inside one integrated disposable: you set the counterbalance once, and after the first extraction the platelet-plasma suspension goes back into the same device for the second spin. Two arguments follow. The first needs no interpretation: one disposable to stock and one counterbalance to get right instead of two.

The second is a handling rationale: fewer transfers mean less platelet-to-plastic contact across the process. Platelets adhere to plastic, so the reasoning is that an integrated kit gives up fewer of them along the way. Presented plainly, that is a rationale based on how the workflow is built, not a published head-to-head recovery comparison between the two kits.

The case for Pure Two PRP

Pure Two PRP splits the job across a separator device and a concentrator device, with two separate balance steps. It is a widely used, established two-step kit, and for a team already trained and standardized on that protocol, staying put is a reasonable call. Platelet counts are comparable to SP.

Which one fits your practice?

Simplest bench and one thing to stock. PurePRP SP, one integrated disposable, counterbalanced once.
Already trained on the two-device protocol. Pure Two PRP, comparable counts on the workflow you run today.
Either way, both run on the same Sapphire centrifuge in 30, 60, and 120 mL, so you can standardize on one without a second machine.

Want the full lineup, including single-spin and the bone marrow, adipose, and A2M systems, side by side?

Compare all PRP systems

Get pricing on SP or Pure Two

Tell us which you're leaning toward and your case volume. A U.S.-based specialist sends pricing within one business day.

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PRP Direct distributes 510(k)-cleared autologous blood-processing devices. Manufacturer specifications are not claims of clinical efficacy of the prepared biologic. This page is general education for clinicians evaluating equipment and is not medical advice.

What these devices are cleared for

Emcyte's instructions for use define the labeled indication for the PurePRP Supraphysiologic Concentrating System as follows, quoted verbatim:

"The PurePRP^® Supraphysiologic Concentrating System is designed to be used for the safe and rapid preparation of autologous platelet rich plasma (PRP) from a small sample of blood at the patient's point of care. The PRP is mixed with autograft and allograft bone prior to application to an orthopedic site to improve bone graft handling characteristics."

The same document states: "The PRP prepared by this device has not been evaluated for any clinical indications." It also states that the safety and effectiveness of the device for in vivo indications such as bone healing and hemostasis have not been established, and that the PRP prepared by the device is not indicated for delivery to the patient's circulatory system.

Any application other than the labeled indication falls outside it. That is not unusual in this field, and it is not something PRP Direct can authorize, recommend, or direct. It rests on the independent clinical judgment of a licensed physician, exercised under their own license and their own informed-consent process. We sell equipment and publish what the manufacturer publishes about it. We do not advise on clinical application.

PRP Direct is a distributor of Emcyte point-of-care blood-processing devices. Emcyte states these systems are 510(k)-cleared as blood-processing devices; clearance covers how a device processes blood, it is not a clearance of the prepared PRP to treat any condition, and no PRP therapy is FDA-approved for a specific indication. Manufacturer specifications are reproduced as the manufacturer's statements, have not been independently verified by PRP Direct, and are not claims of clinical efficacy. Manufacturers revise specifications without notice, and the instructions for use packaged with your kit supersede anything published here. Nothing on this page is dosing, protocol, clinical, or medical advice, and nothing here should be relied upon in making a clinical decision. Product names and trademarks belong to their respective owners.